Mechanism of action

MECHANISM OF ACTION - Modern aspects of electrotherapy

In the base of electrotherapeutic action and in particular – of the electrotherapeutic action of SCENAR, lies the refectory neuro-adaptive mechanism of adaptation, which ensures (maintains and restores), the dynamic equilibrium of human organism, both with the surrounding environment and with its internal environment – the homeostasis, i.e. the state of being healthy. The regulation of all vital functions is realized due to the close connection and interaction of the nervous and the humor-endocrine systems, the effects of which are mediated through a release from the neural cells of biologically active substances called neuromediators (NM):
  • classical neuromediators – amines (acetylcholine, noradrenaline, etc.) and amino-acids (glutamine, asparagin, etc.), which are characteristic of the thick myelinated A- and B-neural fibres and have clearly defined (quick and short) physiological effect;
  • neutopeptides (NPs) – the largest at present and most important from physiological and medical point of view group of NM – endorphins, enkephalines, neurotensine, bradikinine and a great number of others (more than 2000 NPs). The NPs are the main NM for the thin nonmyelinated and difficult for excitation (activation) C-fibres. These peptidergic (producing NPs) fibres make up the major part (more than 70%) of the nervous trakts. Contemporary science has already unambiguously proved that due to their specific properties (long lasting and extended in time and distant in place effect, formation of complex regulative chains and cascades for control of multiple physiological functions, powerful analgesic effect etc.) the NPs – these endogen own for the human body pharmaceuticals carry out all autoregulatory and autotherapeutic processes focused on maintaining and restoration of homeostasis, i.e. the state/ condition of health in the organism.
That is why, the main goal of electrotherapy is that a maximal part of the nervous tissue is activated, and first of all the peptidergic (producing NPs) C-fibres, which should bring to the release of an effective dose of NPs, necessary for overcoming the existing in the organism disturbances. This goal can be achieved only to a certain extent by the conventional methods of electrotherapy: 
  • due to the non-physiological in form and duration character of their impulses, an excitation of the thick A-fibres is mainly achieved, while it is practically impossible to activate the extremely thin C-fibres without risk of damaging the rest of the tissues. 
  • the process of habituation of the organism to similar impulses brings to comparatively quick decrease of their therapeutic effect.